Hollywood icon George Clooney is facing a health setback at the 2025 Venice Film Festival, where his latest film Jay Kelly is set to premiere. The 64-year-old actor was notably absent from several key events on August 27, including the film’s press conference, after his representative confirmed he was down with a “bad sinus infection.” Despite his illness, festival organizers hinted that Clooney “should” be in attendance at the movie’s premiere, much to the hope of his co-stars Adam Sandler, Riley Keough, and Laura Dern.

Clooney arrived in Venice alongside his wife Amal Clooney on August 26, turning heads as the couple greeted fans while cruising through the canals. The actor has described his role in Jay Kelly—a Noah Baumbach film following a European journey between Jay (Clooney) and his manager Ron (Sandler)—as one of the most vulnerable performances of his career. For Clooney, embracing aging on screen is no longer a challenge but a chance to explore new depth as an actor.

While fans eagerly await his red-carpet appearance, Clooney remains grateful for the unwavering support of his wife of nearly 11 years, Amal. “She’s the bravest human being I’ve ever met in my life,” he shared in a recent interview, describing their partnership as his greatest fortune. Whether or not he makes the premiere, Clooney’s presence at the festival continues to shine through his work, his words, and the admiration of those around him.